Robyn Exton, Jill O'Sullivan, Mook Phanpinit
Robyn is the CEO & Founder of HER. Find her on Twitter.
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Robyn Exton, Jill O'Sullivan, Mook Phanpinit
Jan 13, 2026
Have you ever found yourself asking, “What should trans people know about safe sex?”
Feeling seen, safe, and satisfied isn’t too much to ask: it’s foundational. Sexual health for trans women deserves to be affirming, stigma-free, and rooted in pleasure, choice, and agency.
This guide shares practical, real-world safe sex tips for trans women and their partners. From barrier methods and PrEP to communication and post-surgical care, these are tools you can use to protect your body while keeping pleasure and sexual wellness at the front of mind.
The need for trans specific sexual health information is real, and more important now than ever before. A systematic review found an HIV prevalence of 14.1 percent among U.S. trans women, which is way higher than in the general population (systematic review of U.S. trans women). Access to clear, relevant sexual health information for trans women helps close that gap and supports safer, more confident intimacy.
HER is built for safe, inclusive, emotionally fluent connections among trans, lesbian, bisexual, and nonbinary people. We center consent, communication, and community care, with tools that let you define your identity, set boundaries, and report concerns on your terms.
Whether you are dating, hooking up, or building something deeper, you deserve spaces where your safety and agency are non-negotiable. Period.
For broader dating safety guidance, see HER Dating Safety Tips.
When it comes to trans women’s sexual health, we’ve got to talk about barriers. Barrier methods are physical tools like external or internal condoms, dental dams, and gloves. They reduce the exchange of bodily fluids and lower skin-to-skin STI transmission. They matter for all bodies, identities, and all types of sex, including vaginal, anal, and oral sex, and remain important after vaginoplasty or during receptive anal sex.
Use an external condom for vaginal or anal intercourse. For oral sex on vulvas or neovaginas, use a dental dam or a cut-open condom.
Replace condoms or gloves when switching partners, body parts, or toys. Even if you are on PrEP, barriers still matter. PrEP helps prevent HIV, but barriers are what reduce the risk of many other STIs (Trans Safer Sex Guide).
Safe sex for trans women should include regular STI testing. Testing is routine self-care. It protects you and your partners.
Aim for at least an annual screening, and every three to six months if you have new or multiple partners or higher risk exposures (TransLash guide to trans sex).
Common tests include HIV, syphilis, gonorrhea, chlamydia, and hepatitis. Because HIV prevalence among U.S. trans women is significantly higher than in the general population, regular screening is a smart baseline, not an overreaction (systematic review of U.S. trans women).
Look for LGBTQ+ competent providers who respect your pronouns, body, and boundaries (Mayo Clinic advice on transgender health visits).
Sexual health education for trans people isn’t just about the physical stuff. Clear communication builds trust, safety, and better sex.
Before getting intimate, it can help to:
If a partner resists protection or dismisses your boundaries, pause. State what you need, offer alternatives, or end the encounter. HER centers emotionally safe connections. Your comfort is reason enough to slow down or stop. No is a complete sentence, and there is nothing wrong with walking away when your safety cannot be respected.
Lubricants reduce friction, prevent microtears, and support pleasure. They’re especially important for anal sex and for people with neovaginas or those on hormones, which can affect natural lubrication production.
Rectal tissue is delicate, and microtears can increase STI and HIV risk. Use plenty of lube (even more than you think you’ll need, trust us) and reapply as needed (Caracole trans sexual health resource).
Lube types at a glance:
| Lube type | Pros | Cons | Best use cases |
| Water-based | Condom-safe; easy to clean; compatible with toys | Dries faster; may require reapplication | Oral, vaginal, anal; all condom types |
| Silicone-based | Long-lasting; very slick; condom-safe | Can degrade some silicone toys; harder to wash off | Anal, longer sessions, water play |
| Oil-based | Long-lasting; great for massage | Breaks down latex; not condom-safe; can irritate | Solo play without latex; avoid with latex condoms |
Note: Oil-based products weaken latex and can make condoms less effective.
PrEP is a daily pill that dramatically lowers the chance of acquiring HIV. It’s recommended for people at higher HIV risk and does not negatively interact with estrogen or hormone blockers (TransLash guide to trans sex).
PrEP does not protect against other STIs, so pairing it with condoms and regular testing offers broader protection.
PrEP basics for trans women:
Hygiene supports safer, more comfortable sex, especially if you’re healing from surgery or managing sensitive tissue.
STIs and other infections can spread through shared toys.
Always follow the manufacturer’s cleaning instructions and store toys fully dry.
Oral sex can transmit herpes, gonorrhea, HPV, and hepatitis A.
To lower risk, use:
Rimming carries added risk for hepatitis A and bacterial STIs. Use barriers and practice thorough hygiene before and after. Vaccinations for hepatitis A, hepatitis B, and HPV add another layer of protection.
Gender affirming surgeries like vaginoplasty, breast augmentation, or facial feminization support alignment with your gender identity. Healing timelines vary, and your surgeon’s guidance should always come first (practical safer sex hygiene guide).
General timelines may look like this:
Vaginoplasty
Breast augmentation
Facial feminization
Avoid oral or penetrative sex with tissue that is healing, inflamed, or painful. Seek care right away if anything feels off. You know your body the best: trust it!
Watch for signs like pain or burning during urination, sores, unusual discharge, itching, fever, or rash after sex.
Quick testing and treatment protect both you and your partners and help prevent complications or reinfection (practical safer sex hygiene guide).
Advocate for yourself. If a provider isn’t trans competent or respectful, ask for another doctor or find a clinic that is. Let recent partners know any diagnoses right away, so they can test and treat too.
Use condoms and dental dams for all types of sex, get tested regularly, and consider PrEP for added HIV protection. Open communication about boundaries and protection strengthens safety.
Feminizing hormones do not prevent STIs or pregnancy. Use barriers and contraception when relevant.
Use condoms or dental dams, choose water or silicone-based lube, and follow your surgeon’s guidance before resuming sex after surgery. Change barriers and reapply lube when switching acts.
Share your needs and testing history in a calm moment. Ask about theirs. Agree on language and protection that feels affirming. If boundaries are not respected, pause or walk away.
At least annually, and every three to six months if you have new or multiple partners or higher risk exposures. A trusted provider can help tailor a schedule to your sex life.
Robyn Exton, Jill O'Sullivan, Mook Phanpinit
Robyn is the CEO & Founder of HER. Find her on Twitter.